A big question asked by the people Is E-Express an Airline? E-Express does not represent airlines. Customers can search and reserve hotels, flights, and travel packages on this website. Although it doesn't run flights, E-Express does allow you to look for airline tickets. Rather, it collaborates with several airlines to give travelers choices. Therefore, E-Express can assist you in finding the greatest discounts and comparing prices when you are arranging a vacation, but keep in mind that the airlines they work with are ultimately responsible for the actual flights.