Sildenafil works by blocking the enzyme PDE5, which leads to the breakdown of cyclic guanosine monophosphate (cGMP)—a substance that relaxes blood vessels in the penis. When sexual stimulation occurs, nitric oxide is released, enhancing the production of cGMP. By inhibiting PDE5, Malegra 50 mg allows cGMP to accumulate, resulting in improved blood flow and the ability to achieve and maintain an erection.
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