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Deadfire isn’t just a standalone skill; it works incredibly well when combined with other elemental damage mechanics in buy path of exile 2 orb. Players can enhance Deadfire’s potency by pairing it with fire-based damage over time effects, such as Ignite, or even stacking it with other area-effect skills like Scorching Ray or Firestorm. This synergy increases the total damage dealt while also amplifying the strategic potential of Deadfire.

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For instance, Deadfire’s lingering burn effect can be combined with the "Elemental Overload" passive skill, which boosts elemental damage after inflicting a critical hit. Since Deadfire often leaves enemies burning for extended periods, crit-focused builds can significantly increase their damage output by leveraging both the burn and elemental damage bonuses. This makes Deadfire an essential component in many end-game builds.

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Additionally, Deadfire can be synergized with debuffs that increase the vulnerability of enemies to fire damage, such as "Flammability" or "Elemental Weakness." These debuffs make enemies more susceptible to both the initial and lingering effects of Deadfire, maximizing the overall damage output. Combining Deadfire with support gems that increase damage over time or area of effect (AoE) also makes it a formidable tool for both clearing packs and boss fights.